Pediatric Bipolar
Disorders Program

Publications

DelBello MP, Chang K, Welge JA, Adler CM, Rana M, Howe M, Bryan H, Vogel D, Sampang S, Delgado SV, Sorter M, Strakowski SM. (2009) A double-blind, placebo-controlled pilot study of quetiapine for depressed adolescents with bipolar disorder. Bipolar Disord. 11(5):483-93.

Wagner, KD, Redden, L, Kowatch, RA, Wilens, TE, Segal, S, Chang, KD, Wozniak, P, Vigna, NV, Abi-Saab, W, Saltarelli, M (2009) A double-blind, randomized, placebo-controlled trial of divalproex ER in the treatment of bipolar disorder in children and adolescents. J Am Acad Child Adolesc Psychiatry. 48(5):519-32.

Chang, KD (2009) Challenges in the diagnosis and treatment of pediatric bipolar depression. Dialogues Clin Neurosci. 11(1):73-80.

Simeonova, DI, Jackson, V, Atalla, A, Karchemskiy, A, Howe, M, Adleman, N, Chang, KD (2009) Subcortical volumetric correlates of anxiety in familial pediatric bipolar disorder: A preliminary investigation. Psychiatry Res. 173(2):113-20.

Barnea-Goraly, N, Chang, KD, Karchemskiy, A, Howe, M, Reiss, AL (2009) Limbic and corpus callosum aberrations in adolescents with bipolar disorder: A tract-based spatial statistics analysis. Biol Psychiatry. 66(3):238-44.

Chang, KD, Karchemskiy, A, Kelley, R, Howe, M, Garrett, A, Adleman, N, Reiss, AL (2009) Effect of divalproex on brain morphometry, chemistry, and function in youth at high-risk for bipolar disorder: a pilot study.J Child Adolesc Psychopharmacol 19:51-9.

Garrett A & Chang, KD (2008). The role of the amygdala in bipolar disorder development. Dev Psychopathol 20(4):1285-96.

Miklowitz, DJ & Chang, KD (2008).  Prevention of bipolar disorder in at-risk children: theoretical assumptions and empirical foundations.  Development and Psychopathology, 20(3), 881-897.

Chang, KD (2008) The bipolar spectrum in children and adolescents: developmental issues, J Clin Psychiatry 69(3):e9.

Chang, KD, Wagner, C, Garrett, A, Howe, M, Reiss, A (2008) A preliminary functional magnetic resonance imaging study of prefrontal-amygdalar changes in adolescents with bipolar depression treated with lamotrigine, Bipolar Disord 10:426-431.

Singh, M & Chang, KD (2007) Impact of Bipolar Disorder on Selected Areas of Pediatric Development: A Research Update, Pediatric Health 1(2):199-216

Madaan, V & Chang, KD (2007) Pharmacotherapeutic strategies for pediatric bipolar disorder, Expert Opinion Pharmacotherapy Aug;8(12):1801-19.

Chang, KD, Howe, M., Gallelli, K., Miklowitz, D. J. (2007) Prevention of pediatric bipolar disorder: Integration of neurobiological and psychosocial processes, Ann New York Acad Sciences1094:235-47.

Baumer, F, Howe, M, Gallelli, K, Chang, KD, (2006) Antidepressant-induced mania in pediatric bipolar disorder: characteristics, risk factors, and the serotonin transporter gene, Biol Psychiatry 60(9):1005-1012.

Chang, KD, Adleman, N, Wagner, C, Barnea-Goraly, N, Garrett, A (2006) Will neuroimaging ever be used to diagnose pediatric bipolar disorder? Dev Psychopathol 18(4): 1133-46.

Chang, KD (2006) Neurodegeneration in pediatric mood disorders: supporting evidence and the case for neuroprotection, Clinical Neuropsychiatry 3(3):184-93.

Chang, KD, Saxena, K, Howe, M (2006) Lamotrigine for the treatment of adolescent bipolar depression, J Amer Acad Child Adolesc Psychiatry 45(3):298-304.

DelBello, MP, Chang, KD (2005) Bipolar disorder in children and adolescents – are we approaching the final frontier? Ed., Bipolar Disorders 7:479–482.

Chang, KD, Karchemskiy, A, Barnea-Goraly, N, Garrett, A, Simeonova, D, Reiss, AL.  (2005), Decreased amygdalar gray matter volume in pediatric familial bipolar disorder, J Am Acad Child Adolesc Psychiatry 44:565-573.

Simeonova, DI, Strong, C, Ketter, T., Chang, KD (2005), Creativity in familial bipolar disorder, J Psychiatry Res 39(6):623-631.

Chang, KD, Adleman, N, Dienes, K, Reiss, AL.  (2004), Anomalous Prefrontal-Subcortical Activation in Familial Pediatric Bipolar Disorder: An fMRI Investigation, Arch Gen Psychiatry 61:781-792.

Chang, KD, Steiner, H, and Ketter, TA.  (2003), Studies of Children and Adolescents at High Risk for Bipolar Disorder, Am J Med Genetics (Semin Med Genet) 123C:26-35.

Chang, KD, Adleman, N, Dienes, K, Reiss, AL, and Ketter, TA.  (2003), Bipolar Offspring: A Window Into Bipolar Disorder Evolution, Biological Psychiatry 53:945-951.

Chang, KD, Adleman, N, Dienes, K, Reiss, AL, and Ketter, TA.  (2003), Decreased N-acetyl aspartate Levels in Pediatric Bipolar Disorder, Biological Psychiatry 53:1059-1065.

Chang, KD, Dienes, K, Blasey, C, Adleman, N, Steiner, H, and Ketter, TA.  (2003), Divalproex in the treatment of bipolar offspring with mood and behavioral disorders, J Clin Psychiatry 64:936-942.

Chang KD, Blasey C, Ketter TA Steiner H. (2001), Family environment of children and adolescents with bipolar parents, Bipolar Disorders 3: 73–78.

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